Duquesnoy Publications On HLA Epitopes


1. Duquesnoy, RJ: HLAMatchmaker: A Molecularly Based Donor-Selection Algorithm for Highly Allosensitized Patients. Transplantation Proc. 33: 493-497, 2001
2. Duquesnoy, RJ: HLAMatchmaker: A Molecularly Based Algorithm For Histocompatibility Determination I Description of the Algorithm, Human Immunology 63: 339-352, 2002
3. Duquesnoy, RJ and Marrari, M: HLAMatchmaker: A Molecularly Based Algorithm For Histocompatibility Determination II Verification of the Algorithm and Determination of the Relative Immunogenicity of Amino Acid Triplet-Defined Epitopes, Human Immunology 63: 353-263, 2002
4. Duquesnoy, RJ, HLAMatchmaker: A Molecularly Based Algorithm For Histocompatibility Determination. ASHI Quarterly, 2002: p. 60-62
5. Duquesnoy, RJ , Takemoto S, de LangeP, Doxiadis IIN, Schreuder GMTh , Persijn, G and Claas FJH: HLAMatchmaker: A Molecularly Based Algorithm For Histocompatibility Determination III Effect of matching at the HLA-A,B amino acid triplet level on kidney transplant survival. Transplantation 75: 884-889, 2003
6. Duquesnoy, RJ, Howe J, and Takemoto, S: HLAMatchmaker: A Molecularly Based Algorithm For Histocompatibility Determination. IV An Alternative Strategy to Increase the Number of Compatible Donors for Highly Sensitized Patients, Transplantation 75: 889-897, 2003
7. Duquesnoy, RJ, Witvliet M, Doxiadis I IN, de Fijter H and Claas FHJ: HLAMatchmaker-Based Strategy to Identify Acceptable HLA Class I Mismatches for Highly Sensitized Kidney Transplant Candidates, Transplant International 7: 31-38, 2004
8. Adeyi OE, Girnita A, Howe J, Marrari M, Awadalla Y, Askar M, Martell J, Zeevi A, Shapiro R, Nalesnik M, Rhandawa P, Demetris AJ, and Duquesnoy RJ: Serum Analysis After Kidney Transplant Nephrectomy Reveals Restricted Antibody Specificity Patterns Against Structural HLA Class I Mismatches, Transplant Immunology 14: 53-62, 2005
9. Duquesnoy, RJ and Claas, FHJ: Is the Application of HLAMatchmaker Relevant in Kidney Transplantation? (Letter to the Editor), Transplantation 79: 250-251, 2005
10. Duquesnoy RJ, Mulder A, Askar M, Fernandez-Vina M, and Claas FHJ: HLAMatchmaker-Based Analysis of Human Monoclonal Antibody Reactivity Demonstrates the Importance of an Additional Contact Site for Specific Recognition of Triplet-Defined Epitopes, Human Immunology 66: 749-761, 2005
11. Zeevi A, Girnita A, and Duquesnoy R: HLA antibody analysis: sensitivity, specificity and clinical significance in solid organ transplantation. Immunol. Res. 36:255-64, 2006

12. Duquesnoy RJ: The HLA system and histocompatibility testing for organ transplantation. In Pediatric Transplantation (Eds. Fine R, Webber S, Harmon W, Kelly D and Olthoff K) 2nd Edit (Blackwell Publishing, NY) In Press, 2006
13. Duquesnoy RJ: A structurally based approach to determine HLA compatibility at the humoral immune level. Human immunology 67: 847-862, 2006
14. Duquesnoy, RJ and Claas FHJ: Progress Report of 14th International Histocompatibility Workshop Project on the Structural Basis of HLA Compatibility, Tissue Antigens 69 (Suppl. 1): 1-5, 2007
15. Duquesnoy, RJ and Askar, M: HLAMatchmaker: A Molecularly Based Algorithm for Histocompatibility Determination. V. Eplet Matching for HLA-DR, HLA-DQ and HLA-DP, Human immunology 68: 12-25, 2007
16. Duquesnoy, RJ: “Match and Treat”, An Effective Strategy for Transplanting Highly Sensitized Pediatric Transplant Candidates? (Invited Editorial), Pediatric Transplantation 11: 3-4, 2007
17. Duquesnoy, RJ : Structural Epitope Matching for HLA Alloimmunized Thrombocytopenic Patients: A New Strategy to Provide More Effective Platelet Transfusion Support? Transfusion 48: 221-227, 2008
18. Duquesnoy RJ, Awadalla Y, Lomago J, Jelinek L, Howe J, Zern D, Hunter B, Martell J, Girnita A and A Zeevi: Retransplant Candidates Have Donor-Specific Antibodies that React with Structurally Defined HLA-DR,DQ,DP Epitopes. Transplant Immunology 18: 352-360, 2008
19. Duquesnoy, RJ : Update on HLAMatchmaker: a Molecularly Based Algorithm for Histocompatibility Determination at the Epitope Level, EFI Newsletter, Fall 2007 and ASHI Quarterly 2007: p.74-79
20. Duquesnoy RJ, Spellman S, Haagenson M, Wang T, Horowitz M and Oudshoorn M: HLAMatchmaker-Defined Triplet Matching Is Not Associated with Better Survival Rates of Patients with Class I HLA Allele Mismatched Hematopoietic Cell Transplants from Unrelated Donors. Biol. Blood & Marrow Transplantation 14:1064-1071, 2008
21. Duquesnoy RJ: HLA Class II Antibodies and Transplant Outcome (Invited Analysis and Commentary), Transplantation 86:638-640, 2008
22. Duquesnoy, RJ: Clinical Usefulness of HLAMatchmaker in HLA Epitope Matching for Organ Transplantation, Curr Opinion Immunol. (FJH Claas and RJ Duquesnoy, Eds), 20:1-8 , 2008
23. Duquesnoy RJ, Mostecki J, Hariharan J, and Balasz I: A Structurally Based Epitope Analysis of MICA Antibody Specificity Patterns. Human Immunol. 69: 826-832, 2008
24. Marrari, M and Duquesnoy, RJ: Why can Sensitization by a HLA-DR2 Mismatch lead to Antibodies that react also with HLA-DR1? Human Immunol. 70: 403-9, 2009
25. Duquesnoy RJ and Marrari M: Correlations between Terasaki’s HLA class I epitopes and HLAMatchmaker-defined eplets on HLA-A,B and -C antigens, Tissue Antigens 74: 117-133, 2009
26. Marrari M and Duquesnoy, RJ: Correlations between Terasaki’s HLA class II epitopes and HLAMatchmaker-defined eplets on HLADR and DQ antigens, Tissue Antigens 74: 134-146, 2009
27. Duquesnoy RJ and Marrari M: HLAMatchmaker-Based Definition of Structural HLA Epitopes Detected by Alloantibodies, Curr Opinion in Transplantation 14:403-9, 2009
28. Marrari M and Duquesnoy RJ: Detection of donor-specific HLA antibodies in kidney transplant patients before and after removal of a rejected kidney transplant, Transplant Immunology, 22: 105-109, 2010
29. Lomago J, Jelenik l, Zern D, Howe I, Martell J, Zeevi A and Duquesnoy RJ: How did a Patient Who Types for HLA-B*4403 Develop Antibodies that React with HLA-B*4402? Human immunology, 71: 176-178, 2010
30. Marrari M, Mostecki J, Mulder A, Claas F, Balazs and Duquesnoy RJ: Human Monoclonal Antibody Reactivity with HLA Class I Epitopes Defined by Pairs of Human Monoclonal Antibody Reactivity with HLA Class I Epitopes Defined by Pairs of Mismatched Eplets and Self Eplets, Transplantation 90: 1468-72, 2010
31. Duquesnoy RJ and Marrari M: Detection of Antibodies against HLA-C Epitopes in Patients with Rejected Kidney Transplants, Transplant Immunol 24: 164-71, 2011
32. Duquesnoy RJ: Antibody-Reactive Epitope Determination with HLAMatchmaker and Its Application in Transplantation (Invited review), Tissue Antigens 77: 525-534, 2011
33. Duquesnoy RJ: The antibody response to an HLA mismatch: a model for nonself-self discrimination in relation to HLA epitope immunogenicity (Invited Article), Int J Immunogenetics, 39:1-9, 2011
34. Marrari M, Conca R, Praticò-Barbato L, Amoroso A and Duquesnoy: RJ: Brief Report: Why did two patients who type for HLA-B13 have antibodies that react with all Bw4 antigens except HLA-B13? Transplant Immunology, 25: 217-220, 2011
35. Duquesnoy RJ: Humoral Alloimmunity in Transplantation: Relevance of HLA Epitope Antigenicity and Immunogenicity, Frontiers in Transplantation and Alloimmunity, 2: 59, 2011 published online
36. Zeevi A, Marrari M, Feingold B, Webber S and Duquesnoy RJ: HLA epitope analysis to assess complement and non-complement binding donor specific antibody repertoire in a pediatric heart transplant recipient, Hum Immunol, 73: 48-51, 2012
37. Duquesnoy RJ, Marrari M, Mulder A, Claas FJH, Mostecki J and Balazs I: Structural Aspects of HLA Class I Epitopes Detected by Human Monoclonal Antibodies, Human Immunol. 73: 267-277, 2012
38. Duquesnoy RJ, Marrari M, da M. Sousa LCD, de M. Barroso JRP, de SE Aita KM, da Silva AS and do Monte SJH : 16th IHIW: a website for the antibody-defined HLA epitope registry. Int J. Immunogenetics, 40: 54-59, 2013
39. Duquesnoy RJ, Marrari M, Jelenik L, Zeevi A, Claas FHJ and Mulder A: Structural Aspects of HLA Class I Epitopes Reacting with Human Monoclonal Antibodies in Ig-Binding, C1q-Binding and Lymphocytotoxicity Assays, Human Immunology, 74:1271-1279, 2013
40. Duquesnoy RJ: HLA Epitope Based Matching for Transplantation. (Editorial) Transplant Immunology, 31:1-6, 2014
41. Duquesnoy RJ: Update of the HLA Class I Eplet Database in the Website Based Registry of Antibody-Defined HLA Epitopes, Tissue Antigens, 83:382-390, 2014
42. Duquesnoy RJ, Marrari M, Mulder A, da M. Sousa LCD, Da Silva AS, do Monte SJH.: First Report on the Antibody Verification of HLA-ABC Epitopes Recorded in the HLA Epitope Registry. Tissue Antigens 83: 391-400, 2014
43. Duquesnoy RJ, Marrari M, Tambur A, da Mata Sousa LCD, Da Silva AS, do Monte SJH. First Report on the Antibody Verification of HLA-DR, HLA-DQ and HLA-DP Epitopes Recorded in the HLA Epitope Registry. Human Immunology 75:1097-1103, 2014
44. Duquesnoy RJ: HLA epitope based matching for transplantation: the way to go! Terasaki Festschrift, Clinical Transplants 2013, Chapter 53, 441-451, 2014
45. Duquesnoy RJ, Marrari M, Mostecki J, Da Silva AS, da Mata Sousa LCD, do Monte SJH. First Report on the Antibody Verification of MICA Epitopes Recorded in the HLA Epitope Registry, Int J Immunogenetics, 41:370-377, 2014
46. Duquesnoy RJ: Epitope based human leukocyte matching in transplantation(Editorial), Curr Opin Organ Transplantation,19,418-419 , 2014
47. Duquesnoy RJ: HLA Epitope Antigenicity and Immunogenicity, Curr Opin Organ Transplantation, 19, 428-435, 2014
48. Duquesnoy RJ: HLA epitopes and tolerance induction protocols, (Letter to the Editor) Amer J Transplantation, 14:2667, 2014
49. Duquesnoy RJ, Kamoun M, Baxter-Lowe LA, Woodle ES, Bray RA, Claas FHJ, Eckels DD, Friedewald JJ, Fuggle SV, Gebel HM,. Gerlach JA, Fung JJ, Middleton D, Shapiro R, Tambur AR, Taylor CJ, Tinckam K, Zeevi A:Personal Viewpoint: Should HLA Mismatch Acceptability for Sensitized Transplant Candidates Be Determined at the High-Resolution rather than the Antigen Level? Am J Transplant. 15: 923-930, 2015
50. Duquesnoy RJ, Gebel HM, Woodle ES, Nickerson P, Baxter-Lowe LA, Bray RA, Claas. FHJ, Eckels DD, Friedewald JJ, Fuggle SV, Gerlach JA, Fung JJ, Kamoun M, Middleton D, Shapiro R, Tambur AR, Taylor CJ, Tinckam K, Zeevi A: High-Resolution HLA Typing for Sensitized Patients: Advances in Medicine and Science Require Us to Challenge Existing Paradigms, (Letter to the Editor) Am J Transplant, 2015
51. Duquesnoy RJ, Marrari M, Mulder A: Usefulness of the nonself-self algorithm of HLA epitope immunogenicity in the specificity analysis of monospecific antibodies induced during pregnancy, Frontiers in Immunology, Vol 6, May 2015

HLA Epitope-related Publications by Other Investigators


1. Lobashevsky, AL, Senkbeil RW, Shoaf JL, Stephenson AK, Skelton SB, Burke RM, Deierhoi MH, and Thomas JM: The number of amino acid residues mismatches correlates with flow cytometry crossmatching results in high PRA renal patients. Human Immunology 63: 364-74, 2002
2. Dankers MKA, Witvliet MD, Roelen DL, de Lange P, Korfage N, Persijn GG, Duquesnoy RJ, Doxiadis IIN and Claas FHJ: The Number of Amino Acid Triplet Differences between Patient and Donor is Predictive for the Antibody Reactivity Against Mismatched HLA Antigens, Transplantation I28: 1236-1239, 2004
3. Laux G, Mansmann U, Deufel A, et al. A new epitope-based HLA-DPB matching approach for cadaver kidney retransplants. Transplantation 2003; 75:1527–1532
4. Claas FHJ, Witvliet MD, Duquesnoy RJ, Persijn GG and Doxiadis IIN: The Acceptable Mismatch Program as a Fast Tool to Transplant Highly Sensitised Patients Awaiting a Post-Mortal Kidney: Short Waiting Time and Excellent Graft Outcome, Transplantation 78: 190-193, 2004
5. Boehringer D, Reinhard T, Duquesnoy R , Boehringer S, Enczmann J, de Lange P, Claas F, and Sundmacher R : Beneficial Effect of Matching at the HLA-A and B Amino-Acid Triplet Level on Rejection Free Survival in Penetrating Keratoplasty, Transplantation 77: 417-421, 2004
6. Iniotaki-Theodoraki A, Kalogeropoulou E, Apostolaki M, Doxiadis I, and Stavropoulos-Giokas C: Humoral sensitization against rejected grafts: Specific antibodies to graft immunogenic amino acid triplets. Transplant Proc. 36: 1728-1731, 2004
7. Varnavidou-Nicolaidou, A, Doxiadis I, Iniotaki-Theodoraki A, Patargias T, Stavropoulos-Giokas C, and Kyriakides G: HLA class I donor-specific triplet antibodies detected after renal transplantation. Transplantation Proceedings 36: 1732-1734, 2004
8. Laundy GJ, B.A. Bradley, B.M. Rees, M. Younie, and J.M. Hows Incidence and specificity of HLA antibodies in multitransfused patients with acquired aplastic anemia, Transfusion 44:814-825, 2004
9. Young D: HLA-DP antibodies. ASHI Quarterly 2004 p60-62
10. Laux, G, Mytilineos J, and Opelz G: Critical evaluation of the amino acid triplet-epitope matching concept in cadaver kidney transplanation. Transplantation 77: 902-907, 2004
11. Dankers MK, Heemskerk MB, Duquesnoy RJ, Doxiadis II, Oudshoorn M, Roelen DL and Claas FH: HLAMatchmaker algorithm is not a suitable tool to predict the alloreactive cytotoxic T-lymphocyte response in vitro. Transplantation 78:165-7, 2004
12. Takemoto S, Port FK, Claas FHJ and Duquesnoy RJ: HLA Matching for Kidney Transplantation, Human Immunology 65: 1489-1505, 2004
13. Claas FHJ, Dankers MK, Oudshoorn M, van Rood JJ, Mulder A, Roelen DJ, Duquesnoy RJ and Doxiadis IIN: Differential Immunogenicity of HLA Mismatches in Clinical Transplantation. Transplant Immunology 14: 187-191, 2005
14. Doxiadis IIN, Duquesnoy, RJ, and Claas, FHJ: Extending options for highly sensitized patients to receive a suitable kidney graft. Curr. Opin. Immunol. 17: 536-540, 2005
15. Mulder M, Eijsink C, Kester MGD, Franke MEI, Kardol MJ, Heemskerk MHM, et al. Impact of Peptides on the Recognition of HLA Class I Molecules by Human HLA Antibodies. J Immunol 2005;175:5950–7
16. Hulsmeyer M, Chames P, Hillig R, Stanfield R, Held G, Coulie P, et al. A Major Histocompatibility Complex-Peptide-restricted antibody and T Cell Receptor molecules recognize their Target by distinct binding modes. Crystal structure of Human Leukocyte Antigen (HLA)-A1 -MAGE-A1 complex with Fab-Hyb3, J Biol Chem. 2005;280:2972-80
17. Nambiar A, Duquesnoy RJ, Adams S, Zhao Y, Oblitas J, Leitman S, Stroncek D and Marincola F: HLAMatchmaker-Driven Analysis Of Response To HLA Typed Platelet Transfusions In Alloimmunized Patients, Blood 107: 1690-1697, 2006
18. Haririan A, Fagoaga O, Daneshvar H, Morawski K, Sillix D, El-Amm J, West M, Garnick J, Migdal S, Gruber S, and Nehlsen-Cannarella S: Predictive value of HLA epitope matching using HLAMatchmaker for graft outcomes in a predominantly African-American renal transplant cohort. Clinical Transplantation 20: 226-233 2006
19. Cai J, P. I. Terasaki, Q. Mao, T. Pham, N. El-Awar, J.-H. Lee and L. Rebellato: Development of Nondonor-Specific HLA-DR Antibodies in Allograft Recipients Is Associated with Shared Epitopes with Mismatched Donor DR Antigens, Amer J Transplant 2006; 6: 2947–2954
20. Rosenberg, J, Berri R, Jackowski M, Levis D, Nehlsen-Cannarella S, and Oh H: Multi-array antibody screening in detecting antibodies to mismatched HLA in patients awaiting a second transplant. Transplantation Proceedings 38: 3393-3395, 2006
21. Mihaylova, A, Baltadjieva D, Boneva P, Ivanova M, Penkova K, Marinova D, Mihailova S, Paskalev E, Simeonov P, and Naumova E: Clinical Relevance of Anti-HLA Antibodies Detected by Flow-Cytometry Bead-Based Assays—Single-Center Experience. Human Immunology 67: 787–794, 2006

22. El-Awar N, Terasaki PI, Cai J, Deng CT, Ozawa M, Nguyen A, et al. Epitopes of the HLA-A, B, C, DR, DQ and MICA antigens. Clinical Transplants. 2007:175-94

23. Tambur AR, Buckingham M, McDonald L, Luo X. Development of donor-specific and non-donor-specific HLA-DP antibodies post-transplant: the role of epitope sharing and epitope matching. Clinical Transplants. 2006:399-404.
24. Goodman, RS, Taylor C, O’Rourke C, Lynch A, Bradley JA, and Key T: Utility of HLAMatchmaker and single-antigen HLA-antibody detection beads for identification of acceptable mismatches in highly sensitised patients awaiting kidney transplantation. Transplantation 81: 1331-1336, 2006
25. El-Awar N, Lee JH, Tarsitani C, Terasaki PI, El-Awar N, Lee J-H, et al. HLA class I epitopes: recognition of binding sites by mAbs or eluted alloantibody confirmed with single recombinant antigens. Human Immunology. 2007;68(3):170-80.
26. El-Awar NR, Akaza T, Terasaki PI, Nguyen A. Human leukocyte antigen class I epitopes: update to 103 total epitopes, including the C locus. Transplantation. 2007;84(4):532-40.
27. Piazza A, Poggi E, Ozzella G, Borrelli L, Monaco PI, Scornajenghi A, et al. Public epitope specificity of HLA class I antibodies induced by a failed kidney transplant: alloantibody characterization by flow cytometric techniques. Transplantation. 2006;81(9):1298-305.

28. Idica A, Sasaki N, Terasaki P, Idica A, Sasaki N, Terasaki P. HLA matching by amino acid/positions in double and triple combinations. Clinical Transplants. 2006:123-38.

29. Idica A, Sasaki N, Hardy S, Terasaki P, Idica A, Sasaki N, et al. Unexpected frequencies of HLA antibody specificities in the sera of pre-transplant kidney patients. Clinical Transplants. 2006:161-70.
30. Bishara A, Brautbar C, Zamir G, Eid A, Safadi R, Bishara A, et al. Impact of HLA-C and Bw epitopes disparity on liver transplantation outcome. Human Immunology. 2005;66(11):1099-105.
31. Valentini, RP, Nehlsen-Cannarella SL, Gruber SA, Mattoo TK, West MS, Lang C, Imam AA: Intravenous immunoglubulin, HLA allele typing and HLAMatchmaker facilitate successful transplantation in highly sensitized pediatric renal allograft recipients. Pediatr. Transplant. 11: 77-81, 2007

32. Tambur AR, Ching P, Ramon D. Prediction of immunogenic epitopes--is it feasible? Clinical Transplants. 2007:203-10
33. Brooks EG, MacPherson BR and Fung MK: Validation of HLAMatchmaker algorithm in identifying acceptable HLA mismatches for thrombocytopenic patients refractory to platelet transfusions. Transfusion 48: 2159-2165, 2008
34. Kosmoliaptsis V, Bradley JA, Sharples LD, Chaudhry A, Key T, Goodman RS, et al. Predicting the immunogenicity of human leukocyte antigen class I alloantigens using structural epitope analysis determined by HLAMatchmaker. Transplantation 2008;85(12):1817-25.

35. Maruya E, Sasaki N, El-Awar N, Akaza T, Kitawaki J, Saji H, et al. Immunogenic HLA class I epitopes identified by humoral response to pregnancies. Clinical Transplants. 2008:215-27.

36. Deng C-T, Cai J, Ozawa M, El-Awar N. HLA class II DP epitopes. Clinical Transplants. 2007:195-202
37. Deng CT, El-Awar N, Ozawa M, Cai J, Lachmann N, Terasaki PI, et al. Human leukocyte antigen class II DQ alpha and beta epitopes identified from sera of kidney allograft recipients. Transplantation. 2008;86(3):452-9
38. Naumova E, Panchev P, Simeonov PJ, Mihaylova A, Penkova K, Boneva P, Marinov D, Paskalev PE, Simeonov PL, Zlatev A: Organ Transplantation in Bulgaria. Cell Tissue Banking 9:337-342, 2008
39. Cai J, Terasaki PI. Post-transplantation antibody monitoring and HLA antibody epitope identification. Current Opinion in Immunology. 2008;20(5):602-6.
40. Vaidya S, B Hilson, S Sheldon, P Cano, M Fernandez-Vina: DP reactive antibody in a zero mismatch renal transplant pair. Human Immunol 68: 947-949, 2007
41. El-Awar N, Terasaki PI, Nguyen A, Sasaki N, Morales-Buenrostro LE, Saji H, et al. Epitopes of HLA antibodies found in sera of normal healthy males and cord blood. Hum Immunol 70:844-853, 2009
42. Kamoun M, JH. Holmes, AK. Israni, JD. Kearns, V Teal, WP Yang, SE. Rosas, MM. Joffe, H Li, and HI. Feldman: HLA-A amino acid polymorphism and delayed kidneyallograft function. PNAS (2008) 105:18883–18888
43. Kosmoliaptsis V, Chaudhry AN, Sharples LD, Halsall DJ, Dafforn TR, Bradley JA, et al. Predicting HLA class I alloantigen immunogenicity from the number and physiochemical properties of amino acid polymorphisms. Transplantation. 2009;88(6):791-8
44. Cano P, Fernandez-Vina M (2009) Two sequence dimorphisms of DPB1 define the immunologically serologic epitopes. Hum Imm 70:836-843, 2009
45. Zou Y, Qin Z, Silveus A, Fan Y, Stastny P. Polymorphisms of MICA recognized by human alloantibodies. Immunogenetics. 2009;61(2):91-100.
46. Claas FHJ, Rahmel A, Doxiadis IIN. Enhanced kidney allocation to highly sensitized patients by the acceptable mismatch program. Transplantation. 2009;88(4):447-52.

47. El-Awar N, Terasaki M, Cai J, Deng CT, Ozawa M, Lias M, et al. Epitopes of HLA-A, B, C, DR, DQ, DP and MICA Antigens. Clinical Transplants. 2009;2009:295-321.
48. Claas FHJ. Towards selective HLA mismatching in clinical transplantation. Transplantation. 2009;88(6):760-1.
49. Muro M, Gonzalez-Soriano MJ, Salgado G, Lopez R, Boix F, Lopez M, et al. Specific "intra-allele" and "intra-broad antigen" human leukocyte antigen alloantibodies in kidney graft transplantation. Human Immunology. 2010;71(9):857-60
50. Mulder A, Kardol MJ, Arn JS, Eijsink C, Franke MEI, Schreuder GMT, et al. Human monoclonal HLA antibodies reveal interspecies crossreactive swine MHC class I epitopes relevant for xenotransplantation. Molecular Immunology. 2010;47(4):809-15.
51. Billen EVA, Christiaans MHL, Doxiadis IIN, Voorter CEM, van den Berg-Loonen EM. HLA-DP antibodies before and after renal transplantation. Tissue Antigens. 2010;75(3):278-85.
52. Kosmoliaptsis V, Sharples LD, Chaudhry AN, Halsall DJ, Bradley JA, Taylor CJ. Predicting HLA class II alloantigen immunogenicity from the number and physiochemical properties of amino acid polymorphisms. Transplantation. 2011;91(2):183-90.
53. Tambur A, Leventhal JR, Friedewald J, Ramon D. The Complexity of Human Leukocyte Antigen (HLA)-DQ Antibodies and Its Effect on Virtual Crossmatching. Transplantation. 2010;90:1117-24
54. Ravindranath MH, Taniguchi M, Chen CW, Ozawa M, Kaneku H, El-Awar N, et al. HLA-E monoclonal antibodies recognize shared peptide sequences on classical HLA class Ia: relevance to human natural HLA antibodies. Molecular Immunology. 2010;47(5):1121-31
55. El-Awar NR, Terasaki PI, Nguyen A, Lias M, Conger N. New HLA class I epitopes defined by murine monoclonal antibodies. Hum Immunol. 2010;71:456-61.
56. Kosmoliaptsis V, JABradley, CJ. Taylor: Structural Limitations to the Mimetic HLA Epitope Hypothesis (Letter to Editor). Transplantation 87:1263, 2009
57. Thaunat O, Hanf W, Dubois V, McGregor B, Perrat G, Chauvet C, et al. Chronic humoral rejection mediated by anti-HLA-DP alloantibodies: insights into the role of epitope sharing in donor-specific and non-donor specific alloantibodies generation. Transplant Immunology. 2009;20(4):209-11.
58. Suarez-Alvarez B, Alonso-Arias R, Bravo-Mendoza C, Lopez-Vazquez A, Ortega T, Baltar JM, et al. Identification of epitopes and immunodominant regions on the MICA protein defined by alloantibodies from kidney transplant patients. Transplantation. 2009;88(3 Suppl):S68-77.
59. Kosmoliaptsis V, Sharples LD, Chaudhry A, Johnson RJ, Fuggle SV, Halsall DJ, et al. HLA class I amino acid sequence-based matching after interlocus subtraction and long-term outcome after deceased donor kidney transplantation. Human Immunology. 2010;71(9):851-6.
60. Cox ST, Stephens HAF, Fernando R, Karasu A, Harber M, Howie AJ, et al. Major histocompatibility complex class I-related chain A allele mismatching, antibodies, and rejection in renal transplantation. Human Immunology. 2011;72(10):827-34

61. Sasaki N, El-Awar N, Idica A. Effect of amino acid mismatch in the UNOS dataset. Clinical Transplants. 2011:299-309.
62. Poli F, Benazzi E, Innocente A, Nocco A, Cagni N, Gianatti A, et al. Heart transplantation with donor-specific antibodies directed toward denatured HLA-A02:01: a case report. Human Immunology. 2011;72(11):1045-8.
63. Jacob EK, De Goey SR, Gandhi MJ. Positive virtual crossmatch with negative flow crossmatch results in two cases. Transplant Immunology. 2011;25(1):77-81.
64. Cox ST. The relevance and impact of MICA allele mismatching and MICA antibodies on renal transplantation outcome: University College London (UCL); 2011.
65. Böhringer D, Daub F, Schwartzkopff J, Maier P, Birnbaum F, Sundmacher R and Reinhard T: Operational post-keratopasty graft tolerance due to differential HLAMatchmaker matching. Molecular Vision 16: 2362-2367, 2010
66. Pai SC, Lo SC, Lin Tsai SJ, Chang JS, Lin DT, Lin KS and Lin LI: Epitope-based matching for HLA-alloimmunized platelet refractoriness in patients with hematologic diseases. Transfusion 50: 2318-2327, 2010
67. Silva E, Alba A, Castro A, Carrascal M, Buckel E, Aguiló J, Herzog C, Calabrán L, Morales J and Fierro JA: Evaluation of HLAMatchmaker compatibility as predictor of graft survival and presence of anti-HLA antibodies. Transplantation Proc. 42: 266-269, 2010
68. Clark B, N Marsden, K McKinley, A Lewington and C Newstead: Successful kidney transplantation with a well-matched donor despite a positive crossmatch; detection and management of sensitization secondary to an alternate allelic variant of ‘self’ HLA . Nephrology Dialysis Transplantation Plus 4: 258–259, 2011
69. Ravindranath MH, Pham T, El-Awar N, Kaneku H, Terasaki PI. Anti-HLA-E mAb 3D12 mimics MEM-E/02 in binding to HLA-B and HLA-C alleles: Web-tools validate the immunogenic epitopes of HLA-E recognized by the antibodies. Molecular Immunology. 2011;48(4):423-30
70. Sousa LCDM, Sales HLA, Von Glehn C, Silva AS, Santos Neto PA, Castro JAF, et al. EpHLA: An innovative and user-friendly software automating the HLAMatchmaker algorithm for antibody analysis. Transplant Immunol. 2011;25:210-6.
71. Kosmoliaptsis V, Dafforn TR, Chaudhry AN, Halsall DJ, Bradley JA, Taylor CJ. High-resolution, three-dimensional modeling of human leukocyte antigen class I structure and surface electrostatic potential reveals the molecular basis for alloantibody binding epitopes. Human Immunology. 2011;72(11):1049-59.
72. Zielinska H, G. Moszkowska, M. Zielinski, A. Debska-Slizien , B. Rutkowski, and P. Trzonkowski: Algorithm to Manage Highly Sensitized Kidney Transplant Recipients in Poland. Transplant Proceed. 443:2903-2907, 2011
73. Tambur A, Leventhal JR, Friedewald J and Ramon D: The complexity of human leukocyte antigen (HLA)-DQ antibodies and its effect on virtual crossmatching. Transplantation 90: 1117-11124, 2010
74. Sales HLA, LC Demes da Mata Sousa, CQC von Glehn, AS da Silva, PA dos Santos Neto, FF do Nascimento, JAF de Castro, LM do Nascimento, C Kneib, HB Cazarote, DM Kitamura, JRD Torres, L da Cruz Lopes, AAL do Barros, EN da Silva Edlin, FSL de Moura, JMF Watanabe, SJH do Monte. EpHLA software: A timesaving and accurate tool for improving identification of acceptable mismatches for clinical purposes. Transplant Immunology 26: 230-234, 2012
75. Callender CJ, M Fernandez-Vina, MS Leffell, AAZachary:Frequency of HLA-DP-specific antibodies and a possible new cross-reacting group. Hum Immunol 73:175-179, 2012
76. Bosch A, S Llorente, JA Diaz, G Salgado, M LÔpez, F Boix, R LÔpez-HernÂndez, MJ. GonzÂlez-Soriano, JA. Campillo, MR Moya-Quilesa, N Perez-Lopez, A Minguela, L Jimeno, MRA lvarez-LÔpez, M Muro: Low median fluorescence intensity could be a nonsafety concept of immunologic risk evaluation in patients with shared molecular eplets in kidney transplantation. Human Immunol. 73:522-525, 2012
77. Kneib C, von Glehn CQC, Costa FDA, Costa MTBA, Susin MF. Evaluation of humoral immune response to donor HLA after implantation of cellularized versus decellularized human heart valve allografts. Tissue Antigens. 2012;80(2):165-74.
78. Israeli M, Sredni B, Mor E, Zakai C, Tadmor B, Klein T. The immune-modulator AS101 reduces anti-HLA antibodies in sera of sensitized patients: a structural approach. International Immunopharmacology. 2012;13(4):483-9.
79. Ferrari-Lacraz S, Tiercy JM, Villard J. Detection of anti-HLA antibodies by solid-phase assay in kidney transplantation: friend or foe? Tissue Antigens. 2012;79(5):315-25.
80. Tambur AR, Leventhal JR, Zitzner JR, Walsh RC, Friedewald JJ. The DQ barrier: improving organ allocation equity using HLA-DQ information. Transplantation. 2013;95(4):635-40.
81. Otten HG, Calis JJ, Kesmir C, van Zuilen AD, Spierings E. Predicted indirectly recognizable HLA epitopes presented by HLA-DR correlate with the de novo development of donor-specific HLA IgG antibodies after kidney transplantation. Hum.Immunol. 2013;74(3):290-296.
82. Resse M, Paolillo R, Casamassimi A, Cavalca F, Fiorito C, Maiello C, et al. Anti-HLA-A, -B, -DR, -DQB1 and -DQA1 antibodies reactive epitope determination with HLAMatchmaker in multipare awaiting list for heart transplant. Hum Immunol. 2013;74:937–41.
83. Hollenbach JA, Madbouly A, Gragert L, Vierra-Green C, Flesch S, Spellman S, et al. A combined DPA1~DPB1 amino acid epitope is the primary unit of selection on the HLA-DP heterodimer. Immunogenetics. 2012;64(8):559-69.
84. Magee BA, Martin J, Cole MP, Morris KG, and Courtney AE: Effects of HLA-matched blood transfusion for patients awaiting renal transplantation. Transplantation 94:1111-1116, 2012.
85. El-Awar N, Nguyen A, Almeshari K, Alawami M, Alzayer F, Alharbi M, et al. HLA class II DQA and DQB epitopes: Recognition of the likely binding sites of HLA-DQ alloantibodies eluted from recombinant HLA-DQ single antigen cell lines. Human Immunology. 2013;74:1141-52.
86. Honger G, Fornaro I, Granado C, Tiercy JM, Hosli I, Schaub S. Frequency and determinants of pregnancy-induced child-specific sensitization. American Journal of Transplantation. 2013;13(3):746-53.
87. Mikkelsen S, T. Korsholm, A. Iburg, M.S. Petersen, and B.K. Møller. Case Report: Binding of a Clinically Relevant Human Leukocyte Antigen–DQalpha–Specific Antibody in a Kidney Graft Recipient is Inhibited by Donor-Type Human Leukocyte Antigen–DQbeta Chain. Transplant Proceed 45:1209-12, 2013.
88. Wiebe C, Pochinco D, Blydt-Hansen TD, et al Class II HLA Epitope Matching—A Strategy to Minimize De Novo Donor-Specific Antibody Development and Improve Outcomes. Am J Transplant. 2013;13:3114–22.
89. Lutz CT, Al-Attar A, May JR, Jennings CD. Alloantibody to a Bw4 Epitope in a Bw4+ B27:05 Patient. Transplantation. 98: 852-856, 2014
90. Tambur A, Rosati J, Roitberg R, Glotz D, Friedewald JJ, Leventhal JR. Epitope analysis of HLA-DQ antigens: what does the antibody see? Transplantation. 2014;98:157-66.
91. Mierzejewska B, Schroder P, Caitlin, Baum C et al : Early acute antibody-mediated rejection of a negative flow crossmatch 3rd kidney transplant with exclusive disparity at HLA-DP Human Immunology 75:703-708, 2014
92. Lutz CT: Human leukocyte antigen Bw4 and Bw6 epitopes recognized by antibodies and natural killer cells. Curr Opin Organ Transplant 19:436-441, 2014.
93. Wiebe C, Nickerson P. Acceptable mismatching at the class II epitope level: the Canadian experience. Curr Opin Organ Transplant. 19:442–6, 2014.
94. Mallon D, Kosmoliaptsis V, Peacock S, Bradley JA, Taylor CJ. Structural and electrostatic analysis of HLA B-cell epitopes: Inference on immunogenicity and prediction of humoral alloresponses. Curr Opin Organ Transplant. 19:420–7, 2014
95. Salcido-Ochoa F: Human Leucocyte Antigen (HLA) System in Solid Organ Transplantation and Few Novel Concepts on HLA Matching. Recent Trends in Immunology (Editor: Shabir Ahmad Mir Published by SM Online Publishers LLC www.smgebooks.com 2015.
96. Hutchinson JA: HLA typing. Transplantation 99:6-7, 2015
97. Mongkolsuk T, A. Ingsathit, S. Worawichawong, S. Jirasiritham, P. Kitpoka, and D. Thammanichanond: Shared Molecular Eplet Stimulates Acute Antibody-Mediated Rejection in a Kidney Transplant Recipient With Low-Level Donor-Specific Antibodies: A Case Report. Transplant Proceed 46:644-647, 2014
98. Hwang SD, MH Lee, BH Chung, Y Kim, K Han, CW Yang, EJ Oh: Complement-binding donor epitope sharing antibodies in a kidney transplant recipient : Blood Transfusion 2015; 13: 161-3
99. Mallon DH, Bradley JA, Winn PJ, Taylor CJ, Kosmoliaptsis V: Three-Dimensional Structural Modelling and Calculation of Electrostatic Potentials of HLA Bw4 and Bw6 Epitopes to Explain the Molecular Basis for Alloantibody Binding: Toward Predicting HLA Antigenicity and Immunogenicity Transplantation 99:385-390, 2015.
100. Hahn AB, Bravo-Egana V, Jackstadt JL, Conti DJ and R.J.Duquesnoy: HLA-A2 reactive antibodies in a patient who types as HLA-A2: The importance of high resolution typing and epitope-based antibody analysis, Transplant Immunol 32:141-143, 2015.
101. Sapir-Pichhadze R, K. Tinckam, K. Quach, A.G. Logan, A. Laupacis,R. John, J. Beyene, S.J. Kim: HLA-DR and -DQ Eplet Mismatches and Transplant . Glomerulopathy: A Nested Case–Control Study. Amer J Transplant 2015; 15: 137–148.
102. Verduin EP, Schonewille H, Brand A, Haasnoot GW, Claas FHJ, Lindenburg ITM, et al. High anti-HLA response in women exposed to intrauterine transfusions for severe alloimmune hemolytic disease is associated with mother-child HLA triplet mismatches, high anti-D titer, and new red blood cell antibody formation. Transfusion. 2013;53(5):939-47.
103. Tambur AR, Claas FH: HLA Epitopes as Viewed by Antibodies: What Is it All About? Amer J Transplant 15:1148-1154, 2015.
104. Geneugelijk K, Thus KA, Spierings E. Review article: Predicting alloreactivity in transplantation. J. Immunol.Res. 2014; article ID 159479.
105. Thus KA, Ruizendaal MT, de Hoop TA, Borst E, van Deutekom HW, Te Boome L, et al. Refinement of the Definition of Permissible HLA-DPB1 Mismatches with Predicted Indirectly ReCognizable HLADPB1 Epitopes. Biol.Blood Marrow Transplant. 2014;20(11):1705-1710.
106. Thus KA, Te Boome L, Kuball J, Spierings E. Indirectly Recognized HLA-C Mismatches and Their Potential Role in Transplant Outcome. Front.Immunol. 2014;5:210.
107. Lowe D, Shabir S, Buckels J, Muiesan P, Hayden G, Holt A, et al. HLA incompatible combined liver-kidney transplantation: dynamics of antibody modulation revealed by a novel approach to HLA antibody characterisation. Transplant Immunology. 2014;30(1):30-3.
108. van Essen TH , Roelen DL, Williams KA and Jager MJ: Matching for Human Leukocyte Antigens (HLA) in corneal transplantation-To do or not to do. Progr Retinal Eye Res46 (2015) 84-110.
109. Nguyen HD, G Wong, K Howard, FHJ Claas, JC Craig, S Fidler, L D’Orsogna, JR Chapman, A Irish, P Ferrari, FT Christiansen, WH Lim: Modeling the Benefits and Costs of Integrating an Acceptable HLA Mismatch Allocation Model for Highly Sensitized Patients. Transplantation 97:769-774, 2014
110. Middleton D ,J Jones, D. Lowe. Review. Nothing's perfect: The art of defining HLA-specific antibodies. Transplant Immunol. Xxx 2014.
111. Lashley LO, van der Hoorn M-LP, Haasnoot GW, Roelen DL, Claas FHJ. Uncomplicated oocyte donation pregnancies are associated with a higher incidence of human leukocyte antigen alloantibodies. Human Immunology. 2014;75(6):555-60.
112. Haarberg KMK, Tambur AR. Detection of donor-specific antibodies in kidney transplantation. British Medical Bulletin. 2014;110(1):23-34.
113. Filippone EJ, Farber JL. Humoral immunity in renal transplantation: epitopes, Cw and DP, and complement-activating capability – an update. Clin Transplant 29:287-287, 2015